Valentis is one of the few centres in North India to offer dedicated Genetic Counseling clinic. Genetic tests are available to identify the known detrimental mutations (which pose increased risk of cancer) in genes.
Valentis Cancer Hospital has collaborated with Tata Memorial Hospital, Mumbai and MedGenome to perform tests for identifying genetic mutations with next generation DNA sequencing at much lower rates, which can be affordable by the majority of population.
To identify persons with high risk and then prophylactic treatment in the form of medications, surgery, etc.
- BRCA 1&2 for breast and ovarian cancer
- Panel of 94 genes for hereditary cancers
- RB1 for retinoblastoma
- RET mutations for medullary thyroid cancer
- von Hippel-Lindau (VHL) mutations for renal cancer, hemangioblastomas
- NF1 and NF2 for neurofibromatosis
- Specific genes according to the family history
For patients with higher risk of breast cancer, medicines are used which have shown to reduce the risk of breast cancer as
Aspirin has been shown to reduce the risk of cancers in general.
Prophylactic Surgery for breast cancers (Prophylactic Mastectomy) is an option for few patients.
Prophylactic Total Thyroidectomy with Total Parathyroidectomy and Autotransplantation of Parathyroid Glands in persons with
Prophylactic Cholecystectomy (removal of gall bladder in cases of gall stones) esp in endemic areas where incidence of gall bladder cancer is high as in Northern India along the Gangetic belt